Chapter 5 — DNA and Genetic Information · Biology. These are 10 questions from the Magmo3 bank on this lesson, from easy to hard. Solve each one, then open "Show answer and explanation". Magmo3 has 36 questions on this lesson, each with an explanation.
AThe total number of chromosomes inside the nucleus
BThe sequence of nitrogenous bases within the gene
CThe shape of the cell and its outer membrane
DThe size of the nucleus and its nuclear envelope
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Correct answer: (B) The sequence of nitrogenous bases within the gene
Explanation: A gene mutation is a change in the sequence of nitrogenous bases within the gene itself.
Question 2Easy
The agents that cause mutations are called?
AEnzymes
BMutagens
CHormones
DAntibiotics
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Correct answer: (B) Mutagens
Explanation: Mutagens are the agents that increase the rate at which mutations occur.
Question 3Easy
Are all mutations harmful?
AYes, they are all harmful to the organism that carries them
BNo, there are also beneficial or neutral mutations
CNo, they are all beneficial and help the organism adapt
DYes, they are all lethal and cause the death of the cell
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Correct answer: (B) No, there are also beneficial or neutral mutations
Explanation: Mutations may be harmful, neutral (having no effect), or beneficial, and beneficial mutations are the basis of variation and evolution.
Question 4Medium
A substitution mutation means?
AReplacing one nitrogenous base with another in the DNA
BAdding a whole chromosome to the set in the nucleus
CInverting a segment of the chromosome by 180 degrees
DDeleting a segment of the chromosome with its genes
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Correct answer: (A) Replacing one nitrogenous base with another in the DNA
Explanation: In substitution, one nitrogenous base is replaced by another, and this is a type of point mutation.
Question 5Medium
A missense mutation, in its effect?
ADoes not change any amino acid
BOnly prevents transcription
CChanges a single amino acid in the protein
DIncreases the length of the chromosome
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Correct answer: (C) Changes a single amino acid in the protein
Explanation: In a missense mutation the codon changes into one coding for a different amino acid, so a single amino acid in the protein changes.
Question 6Medium
A mutation that occurs in the sex cells (gametes)?
AAlways causes cancer
BIs passed on to the following generations
CDisappears immediately
DAffects only the individual itself
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Correct answer: (B) Is passed on to the following generations
Explanation: A mutation in the sex cells is inherited by the offspring, unlike a somatic mutation, which affects only the individual itself.
Question 7Medium
Inversion of a segment of a chromosome means?
AA segment detaches and moves to another, non-homologous chromosome
BA segment detaches and is permanently lost from the chromosome
CA segment detaches and returns to the same place in reversed order
DA segment is copied and repeated twice on the same chromosome
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Correct answer: (C) A segment detaches and returns to the same place in reversed order
Explanation: In inversion, a segment of the chromosome detaches and returns to its place but with a reversed gene order.
Question 8Hard
Down syndrome results from?
AAn inversion in the X chromosome
BA point mutation in a single gene
CDeletion of chromosome 21
DAn extra copy of chromosome 21 (trisomy)
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Correct answer: (D) An extra copy of chromosome 21 (trisomy)
Explanation: Down syndrome is a numerical chromosomal mutation: 3 copies of chromosome 21 instead of 2, making the total 47 chromosomes.
Question 9Hard
A point mutation changed a codon for an amino acid into a stop codon. The most likely result?
AProducing a protein longer than normal, as translation continues further
BThe gene is duplicated twice, doubling the amount of protein made
CNo change in the protein, since the same amino acid is still added
DProtein synthesis stops early, producing a short non-functional protein
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Correct answer: (D) Protein synthesis stops early, producing a short non-functional protein
Explanation: This is a nonsense mutation: an early stop codon halts translation, producing an incomplete, usually non-functional protein.
Question 10Hard
An insertion of 3 consecutive bases within a gene is most likely to?
AAdd a single amino acid without shifting the reading frame
BStop transcription completely, so no mRNA is made from the gene
CDelete a whole chromosome from the cell nucleus
DShift the entire reading frame, changing every later codon
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Correct answer: (A) Add a single amino acid without shifting the reading frame
Explanation: Adding a number of bases that is a multiple of 3 adds or removes amino acids without shifting the reading frame, so the effect is less than a frameshift.